Yersinia pestis Orientalis in Remains of Ancient Plague Patients
نویسندگان
چکیده
Yersinia pestis DNA was recently detected in human remains from 2 ancient plague pandemics in France and Germany. We have now sequenced Y pestis glpD gene in such remains, showing a 93-bp deletion specific for biotype Orientalis. These data show that only Orientalis type caused the 3 plague pandemics.
منابع مشابه
Genotyping, Orientalis-like Yersinia pestis, and Plague Pandemics
Three pandemics have been attributed to plague in the last 1,500 years. Yersinia pestis caused the third, and its DNA was found in human remains from the second. The Antiqua biovar of Y. pestis may have caused the first pandemic; the other two biovars, Medievalis and Orientalis, may have caused the second and third pandemics, respectively. To test this hypothesis, we designed an original genoty...
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1. Perry RD, Fetherston JD. Yersinia pestis— etiologic agent of plague. Clin Microbiol Rev. 1997;10:35–66. 2. Drancourt M, Houhamdi L, Raoult D. Yersinia pestis as a telluric, human ectoparasite–borne organism. Lancet Infect Dis. 2006;6:234–41. DOI: 10.1016/S14733099(06)70438-8 3. Blanc G, Baltazard M. Recherches expérimentales sur la peste. L’infection du pou de l’homme, Pediculus corporis de ...
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